{"id":27,"date":"2011-12-16T16:50:57","date_gmt":"2011-12-16T16:50:57","guid":{"rendered":"http:\/\/lkksb.lv\/?page_id=27"},"modified":"2024-01-30T15:06:12","modified_gmt":"2024-01-30T13:06:12","slug":"kas-ir-krona-slimiba","status":"publish","type":"page","link":"https:\/\/lkksb.lv\/?page_id=27","title":{"rendered":"Kas ir Krona slim\u012bba"},"content":{"rendered":"\n

KS etiolo\u0123ija un epidemiolo\u0123ija<\/h3>\n\n\n\n
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KS ir viena no IZS form\u0101m. T\u0101 ir hroniska un bie\u017ei progres\u0113jo\u0161a slim\u012bba, kur\u0101 var b\u016bt iesaist\u012bta jebkura gremo\u0161anas trakta da\u013ca no mutes l\u012bdz an\u0101lajai atverei, lai gan visbie\u017e\u0101k iekaisums atrodams tievo zarnu beig\u0101s, resno zarnu s\u0101kum\u0101 vai an\u0101l\u0101s atveres tuvum\u0101. Iekaisums parasti skar zarnu sieni\u0146u vis\u0101 t\u0101s biezum\u0101 un var ar\u012b izplesties \u0101rpus t\u0101s uz blakus eso\u0161iem org\u0101niem. Slim\u012bba parasti s\u0101kas k\u0101 zarnu sieni\u0146as erozijas, no kur\u0101m t\u0101l\u0101k izveidojas nelielas \u010d\u016blas, kas progres\u0113 l\u012bdz daudziem da\u017e\u0101da izm\u0113ra boj\u0101jumiem, s\u0101kot ar maz\u0101m \u010d\u016bl\u0101m l\u012bdz liel\u0101m un dzi\u013c\u0101m \u010d\u016bl\u0101m, ar boj\u0101jumiem da\u017e\u0101d\u0101s zarnu viet\u0101s un zarnu sieni\u0146as piet\u016bkumu, un tam sekojo\u0161u zarnas sa\u0161aurin\u0101\u0161anos. Rakstur\u012bga KS at\u0161\u0137ir\u012bba no otras IZS formas ir zarnu boj\u0101jumu fragment\u0101rais raksturs, kad veseli g\u013cot\u0101das posmi mijas ar iekaisu\u0161iem.<\/p>\n\n\n\n

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KS visbie\u017e\u0101k tiek diagnostic\u0113ta vecum\u0101 no 15 l\u012bdz 29 gadiem.<\/em><\/p>\n<\/blockquote>\n<\/div>\n\n\n\n

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\"Gastro<\/a><\/figure>\n<\/div><\/div>\n<\/div><\/div>\n\n\n\n

KS var rasties jebkur\u0101 dz\u012bves posm\u0101, tom\u0113r t\u0101 visbie\u017e\u0101k tiek diagnostic\u0113ta cilv\u0113kiem vecum\u0101 no 15 l\u012bdz 29 gadiem, nedaudz bie\u017e\u0101k ir sastopama sieviet\u0113m nek\u0101 v\u012brie\u0161iem un bie\u017e\u0101k nov\u0113rojama pils\u0113tu teritorij\u0101s. No katriem 100 000 cilv\u0113kiem no 4 l\u012bdz 214 indiv\u012bdiem b\u016bs KS; no katriem 100 000 cilv\u0113ku katru gadu tiek diagnostic\u0113ti no 0,03 l\u012bdz 16 jauniem gad\u012bjumiem. Slim\u012bba daudz bie\u017e\u0101k ir nov\u0113rojama Eiropas zieme\u013cu da\u013c\u0101, un t\u0101pat t\u0101s att\u012bst\u012b\u0161an\u0101s iesp\u0113ja palielin\u0101s, ja k\u0101dam pirm\u0101s pak\u0101pes radiniekam jau ir KS, vai ja cilv\u0113ks ir ebreju izcelsmes.<\/p>\n\n\n\n

KS c\u0113lo\u0146i<\/h3>\n\n\n\n

Prec\u012bzs KS c\u0113lonis nav zin\u0101ms, tom\u0113r tiek uzskat\u012bts, ka t\u0101 rodas savstarp\u0113ji mijiedarbojoties vides un \u0123en\u0113tiskajiem faktoriem, k\u0101 ar\u012b zarnu bakt\u0113rij\u0101m. Viena lieta ir skaidra: Krona slim\u012bba nerad\u0101s J\u016bsu r\u012bc\u012bbas d\u0113\u013c. J\u016bs neaplipin\u0101j\u0101ties no k\u0101da cita. Simptomu s\u0101kumu neizrais\u012bja kaut kas ap\u0113sts vai iedzerts. To neizrais\u012bja dz\u012bvesveids, kur\u0101 ir daudz stresa. T\u0101d\u0113\u013c, pirmk\u0101rt, nevainojiet sevi!<\/p>\n\n\n\n

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Krona slim\u012bba nerad\u0101s J\u016bsu r\u012bc\u012bbas d\u0113\u013c.<\/em><\/p>\n<\/blockquote>\n\n\n

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\"\"<\/figure>\n<\/div>\n\n\n

Kas ir da\u017ei no iesp\u0113jamajiem c\u0113lo\u0146iem? Vairums ekspertu uzskata, ka skaidrojums ir multifaktori\u0101ls. Tas noz\u012bm\u0113, lai s\u0101ktos Krona slim\u012bba, vair\u0101kiem faktoriem j\u0101darbojas kombin\u0113ti. Tr\u012bs galvenie faktori. par kuriem ir aizdomas, ir \u0161\u0101di:<\/p>\n\n\n\n

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  • vide;<\/li>\n\n\n\n
  • \u0123en\u0113tika;<\/li>\n\n\n\n
  • organisma im\u016bn\u0101s sist\u0113mas slim\u012bga (patolo\u0123iska) reakcija.<\/li>\n<\/ul>\n\n\n\n

    Visticam\u0101kais, ka cilv\u0113ks manto vienu vai vair\u0101kus g\u0113nus, kas vi\u0146u padara jut\u012bg\u0101ku pret Krona slim\u012bbu. Tad kaut kas vid\u0113 ierosina patolo\u0123isku im\u016bnsist\u0113mas atbildes reakciju. (Zin\u0101tnieki v\u0113l nav noteiku\u0161i \u0161o vides \u201cierosin\u0101t\u0101ju\u201d vai \u201cierosin\u0101t\u0101jus\u201d.) Lai kas b\u016btu ierosin\u0101t\u0101js, tas \u201ciesl\u0113dz\u201d im\u016bnsist\u0113mu un t\u0101 uzs\u0101k uzbrukumu KZT sist\u0113mai, un s\u0101kas iekaisums. Neveiksm\u012bg\u0101 k\u0101rt\u0101 im\u016bnsist\u0113ma p\u0113c iekaisuma s\u0101k\u0161an\u0101s vairs \u201cneizsl\u0113dzas\u201d, un t\u0101d\u0113\u013c iekaisums turpin\u0101s, boj\u0101jot gremo\u0161anas org\u0101nus un izraisot Krona slim\u012bbas simptomus.<\/p>\n\n\n\n

    Neviens nezina, kas tie\u0161i izraisa Krona slim\u012bbu. T\u0101pat v\u0113l neviens nevar paredz\u0113t, k\u0101 slim\u012bba p\u0113c diagnostic\u0113\u0161anas ietekm\u0113s noteiktu pacientu. Da\u017eiem pacientiem gadiem ilgi nav nek\u0101du simptomu, bet da\u017eiem ir bie\u017e\u0101ki uzliesmojumi jeb l\u0113kmes. Tom\u0113r viena lieta ir skaidri zin\u0101ma \u2014 Krona slim\u012bba ir hronisks st\u0101voklis. Hroniski st\u0101vok\u013ci ir situ\u0101cijas, kas turpin\u0101s. T\u0101s var kontrol\u0113t ar \u0101rst\u0113\u0161anu, bet nevar iz\u0101rst\u0113t. Tas noz\u012bm\u0113, ka slim\u012bba ir ilgtermi\u0146a. T\u0101pat k\u0101 daudzas lab\u0101k zin\u0101mas slim\u012bbas, piem\u0113ram, cukura diab\u0113tu, augstu asinsspiedienu un sirds slim\u012bbas, to var veiksm\u012bgi \u0101rst\u0113t, bet nevar iz\u0101rst\u0113t. Reiz\u0113m pacientiem var att\u012bst\u012bties smagas un noz\u012bm\u012bgas komplik\u0101cijas, piem\u0113ram, resno zarnu (kolorekt\u0101lais) v\u0113zis, bet tas notiek tikai \u013coti mazam skaitam no visiem IZS pacientiem. P\u0113t\u012bjumos ir pier\u0101d\u012bts, ka pacientiem ar IZS ir t\u0101ds pats paredzamais dz\u012bves ilgums k\u0101 bez IZS. Svar\u012bgi atcer\u0113ties, ka vairums cilv\u0113ku ar Krona slim\u012bbu var dz\u012bvot piepild\u012btu un produkt\u012bvu dz\u012bvi.<\/p>\n\n\n\n

    Person\u0101m, kuras sm\u0113\u0137\u0113, ir divreiz liel\u0101ka iesp\u0113ja att\u012bst\u012bties KS, sal\u012bdzin\u0101jum\u0101 ar nesm\u0113\u0137\u0113t\u0101jiem. Atsevi\u0161\u0137os p\u0113t\u012bjumos k\u0101 KS riska faktori v\u0113l ir nor\u0101d\u012btas antibiotikas, iek\u0161\u0137\u012bgi lietojamie kontracepcijas l\u012bdzek\u013ci, nestero\u012bdi pretiekaisuma l\u012bdzek\u013ci (piem., ibuprof\u0113ns), di\u0113ta (piem., rafin\u0113ts cukurs, tauki un \u0101tr\u0101 \u0113din\u0101\u0161ana), infekcijas un higi\u0113na b\u0113rn\u012bb\u0101, tom\u0113r to loma ir maz\u0101k skaidra, jo liel\u0101kajai da\u013cai cilv\u0113ku, kas saskaras ar \u0161iem faktoriem nekad neatt\u012bst\u0101s KS l\u012bdz\u012bgas s\u016bdz\u012bbas.<\/p>\n\n\n\n

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    Sm\u0113\u0137\u0113\u0161ana palielina KS att\u012bst\u012bbas risku<\/em>.<\/p>\n<\/blockquote>\n\n\n\n

    KS kl\u012bnisk\u0101s paz\u012bmes<\/h3>\n\n\n\n

    Bie\u017e\u0101k sastopamie KS simptomi ir v\u0113dera s\u0101pes (visbie\u017e\u0101k v\u0113dera apak\u0161\u0113j\u0101 labaj\u0101 re\u0123ion\u0101) un nep\u0101rejo\u0161a caureja. Citi simptomi ir svara zudums, \u010d\u016blas mut\u0113, samazin\u0101ta apet\u012bte, drudzis un sv\u012b\u0161ana nakt\u012b. Sal\u012bdzinot ar otru IZS formu \u2013 \u010d\u016blaino kol\u012btu, ret\u0101k v\u0113ro rekt\u0101lu asi\u0146o\u0161anu, t.i., asi\u0146u izdal\u012b\u0161anos no taisn\u0101s zarnas kop\u0101 ar izk\u0101rn\u012bjumiem vai g\u013cot\u0101m. Papildus \u0161iem ar zarnu slim\u012bbu saist\u012btajiem simptomiem, pacientiem v\u0113l var b\u016bt nogurums, mazasin\u012bba jeb an\u0113mija, slikts barojums, iekaisums, s\u0101pes loc\u012btav\u0101s, \u0101das boj\u0101jumi un t\u016bska ac\u012bs vai akn\u0101s. Ja KS att\u012bst\u0101s b\u0113rn\u012bb\u0101, t\u0101 var aizkav\u0113t aug\u0161anu un pubert\u0101ti.<\/p>\n\n\n\n

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    KS bie\u017ei sastopami simptomi ir s\u0101pes v\u0113der\u0101 un nep\u0101rejo\u0161a caureja.<\/em><\/p>\n<\/blockquote>\n\n\n\n

    \"\"<\/figure>\n\n\n\n

    Ja slim\u012bbu ne\u0101rst\u0113, vairumam pacientu ar KS nov\u0113rojami akt\u012bvas slim\u012bbas periodi (recid\u012bvi), kas mijas ar periodiem, kad slim\u012bba ir maz\u0101k akt\u012bva (remisija). Atk\u0101rtoti recid\u012bvi var veicin\u0101t r\u0113taudu veido\u0161anos jeb fibrozi<\/strong>. Fibroze var sa\u0161aurin\u0101t zarnu traktu; \u0161os sa\u0161aurin\u0101jumus d\u0113v\u0113 par strikt\u016br\u0101m <\/strong>vai stenoz\u0113m<\/strong>, kas var rad\u012bt zarnu nosprostojumu, un to d\u0113\u013c var b\u016bt j\u0101veic oper\u0101cija. Turkl\u0101t dzi\u013cas \u010d\u016blas var izspiesties cauri zarnu sieni\u0146ai, radot iekaisumu zarn\u0101m blakus eso\u0161ajos audos. Ja \u0161\u0101d\u0101 viet\u0101 izveidojas sastrutojums, to sauc par abscesu<\/strong>. Ja \u0161ie abscesi veidojas tuvu an\u0101lajai atverei, tie var atv\u0113rties uz \u0101das virsmas ar ej\u0101m, kas tiek d\u0113v\u0113tas par fistul\u0101m<\/strong>. Laika gait\u0101 50% KS pacientu nekontrol\u0113ta iekaisuma d\u0113\u013c izveidosies fistula(-s) vai zarnu strikt\u016bra(-s) un daudziem b\u016bs nepiecie\u0161ama oper\u0101cija. Lai \u0101rst\u0113tu strikt\u016bras, fistulas vai abscesus, bie\u017ei j\u0101veic \u0137irur\u0123iska zarnas izgrie\u0161ana. Tom\u0113r p\u0113c oper\u0101cijas slim\u012bba bie\u017ei atk\u0101rtojas, radot progres\u0113jo\u0161u zarnu funkcion\u0113\u0161anas zudumu un invalidit\u0101ti. \u0160o iemeslu d\u0113\u013c ir \u013coti svar\u012bgi slim\u012bbu s\u0101kt \u0101rst\u0113t iesp\u0113jami agri, kad ir daudz viegl\u0101k p\u0101r to pan\u0101kt kontroli, mazin\u0101t slim\u012bbas izpausmes un nov\u0113rst komplik\u0101cijas.<\/p>\n\n\n\n

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    Svar\u012bgi slim\u012bbu s\u0101kt \u0101rst\u0113t iesp\u0113jami agri, kad ir daudz viegl\u0101k p\u0101r to pan\u0101kt kontroli.<\/em><\/p>\n<\/blockquote>\n\n\n\n

    KS \u0101rst\u0113\u0161anas principi<\/h3>\n\n\n\n

    L\u012bdz \u0161im KS \u0101rst\u0113\u0161ana tika fokus\u0113ta uz slim\u012bbas uzliesmojumu simptom\u0101tisku \u0101rst\u0113\u0161anu. Tom\u0113r p\u0113d\u0113jos gados, vair\u0101k izprotot KS progres\u0113jo\u0161o dabu, ir papla\u0161in\u0101jies \u0101rst\u0113\u0161anas fokuss, saprotot, ka noz\u012bm\u012bg\u0101k par simptom\u0101tisku atvieglojumu un remisijas ieg\u016b\u0161anu, ir zarnu sieni\u0146as sadz\u012b\u0161ana. Tas noz\u012bm\u0113, ka pacientiem, kam s\u016bdz\u012bbas jau ir izzudu\u0161as un kas cit\u0101di j\u016btas labi, medikamenti tiek noz\u012bm\u0113ti ilg\u0101k. Da\u017eiem pacientiem, lai nov\u0113rstu neatgriezenisku zarnu sabruk\u0161anu un ar to saist\u012bt\u0101s komplik\u0101cijas, tiek izsv\u0113rta agr\u012bna iejauk\u0161an\u0101s ar agres\u012bv\u0101m \u0101rst\u0113\u0161anas metod\u0113m.<\/p>\n","protected":false},"excerpt":{"rendered":"

    KS etiolo\u0123ija un epidemiolo\u0123ija KS var rasties jebkur\u0101 dz\u012bves posm\u0101, tom\u0113r t\u0101 visbie\u017e\u0101k tiek diagnostic\u0113ta cilv\u0113kiem vecum\u0101 no 15 l\u012bdz 29 gadiem, nedaudz bie\u017e\u0101k ir sastopama sieviet\u0113m nek\u0101 v\u012brie\u0161iem un bie\u017e\u0101k nov\u0113rojama pils\u0113tu teritorij\u0101s. No katriem 100 000 cilv\u0113kiem no 4 l\u012bdz 214 indiv\u012bdiem b\u016bs KS; […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":7,"menu_order":15,"comment_status":"closed","ping_status":"open","template":"","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-27","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/lkksb.lv\/index.php?rest_route=\/wp\/v2\/pages\/27","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lkksb.lv\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/lkksb.lv\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/lkksb.lv\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/lkksb.lv\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=27"}],"version-history":[{"count":13,"href":"https:\/\/lkksb.lv\/index.php?rest_route=\/wp\/v2\/pages\/27\/revisions"}],"predecessor-version":[{"id":1944,"href":"https:\/\/lkksb.lv\/index.php?rest_route=\/wp\/v2\/pages\/27\/revisions\/1944"}],"up":[{"embeddable":true,"href":"https:\/\/lkksb.lv\/index.php?rest_route=\/wp\/v2\/pages\/7"}],"wp:attachment":[{"href":"https:\/\/lkksb.lv\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=27"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}